AFFIRMO is a recently funded Horizon 2020 five-year research project. Multimorbidity is a common condition in older age, and can substantially influence individuals’ health and quality of life, making management more difficult. A single-disease approach with fragmented care is still prevalent in current healthcare systems despite multimorbidity representing a heterogeneous spectrum of disease combination(s). On…
Contemporary real time system monitoring appears to be the same in each discipline and field of application. Whether it is an aircraft, a chemical plant, a hospitalized patient or an assembly line, the logic is always the same: Deploy a set of sensors Establish admissible upper and lower bounds for each sensor (channel) Define a…
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate. In general, a resting heart rate over 100 beats per minute is accepted as tachycardia in adults. Heart rates above the resting rate may be normal (such as with exercise) or abnormal (such as with electrical problems within the heart). From:…
Models are simplified representations or emulators of reality. They are typically based on empirical data collected conducting experiments. There exist numerous techniques for establishing models based on data. An example of a linear model, built based on 2-dimensional data is illustrated below. The model in this simple case is a straight line. It may be…
Anomaly detection, especially their early detection, is a crucial capability when it comes to operating large complex systems, processes or critical infrastructures. Because it is difficult to make highly complex systems resilient in the face of a multitude of potential often unknown hazards, it is desirable to be able to identify anomalies, malfunctions and attacks…
As the patents on many drugs, which have been launched in the 1990s, will soon expire, the pharmaceutical industry finds itself at a turning point in its evolution, particularly as far as research and development are concerned. As the pipelines of new products are shrinking, the exposure of many companies is increasing. This will surely…
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March 27-th, 2020. The coronavirus has been with us for a few weeks now. The amount of information, speculation, fake news, statistics, extrapolations and more or less credible and sinister and conspiratory theories, is overwhelming. It is easy to have an impression, it is more difficult to have an opinion. It is very easy to…
Just to put things in perspective: “Overall, the CDC estimates that 12,000 and 61,000 deaths annually since 2010 can be blamed on the flu. Globally, the World Health Organization (WHO) estimates that the flu kills 290,000 to 650,000 people per year.” Read full article. The dispersion, 290,000 to 650,000 is significant. We have run a…
Before you start to solve a problem (a numerical problem) you should check its conditioning. An ill-conditioned problem will produce very fragile and unreliable results – no matter how elegant and sophisticated solution you come up with it will be vulnerable. If decisions or strategies are based on fragile outcomes, those decisions and strategies will…
