Multimorbidity – The AFFIRMO Project

AFFIRMO is a recently funded Horizon 2020 five-year research project. Multimorbidity is a common condition in older age, and can substantially influence individuals’ health and quality of life, making management more difficult. A single-disease approach with fragmented care is still prevalent in current healthcare systems despite multimorbidity representing a heterogeneous spectrum of disease combination(s). On…

Complexity Anticipates Ventricular Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate. In general, a resting heart rate over 100 beats per minute is accepted as tachycardia in adults. Heart rates above the resting rate may be normal (such as with exercise) or abnormal (such as with electrical problems within the heart). From:…

On Anomaly Types and Anomaly Detection.

Anomaly detection, especially their early detection, is a crucial capability when it comes to operating large complex systems, processes or critical infrastructures. Because it is difficult to make highly complex systems resilient in the face of a multitude of potential often unknown hazards, it is desirable to be able to identify anomalies, malfunctions and attacks…

Complexity, Drug Toxicity and Drug Design

As the patents on many drugs, which have been launched in the 1990s, will soon expire, the pharmaceutical industry finds itself at a turning point in its evolution, particularly as far as research and development are concerned. As the pipelines of new products are shrinking, the exposure of many companies is increasing. This will surely…