Complexity Engineering Medicine

Ontonix Publishes Article in Biomedical Journal of Science and Technology

Ontonix Publishes Article in Biomedical Journal of Science and Technology on “Complexity Quantification and Comparison of Two Commercially Available Anti-Coagulants”. The article describes how, based on atomic trajectories obtained via Molecular Dynamics simulations, QCM (Quantitative Complexity Management) technology has been utilized to measure and compare the complexity of the molecules of two commercially available and widely used anti-coagulants with very similar side effects. It has been found that the dynamics of one of the two molecules to be significantly more complex.

The experiment described in the paper illustrates how complexity provides a novel mechanism for the analyzing and ranking of drug molecules and may, thus, prove to be a proxy of some of their physio-chemical properties, such as toxicity.

Dowload the article.

Biomedical Journal of Scientific & Technical Research (BJSTR – is a multidisciplinary, scholarly Open Access publisher focused on Genetic, Biomedical and Remedial missions in relation with Technical Knowledge as well.

Established originally in 2005 in the USA, Ontonix is a technology company headquartered in Como, Italy. The unusual technology and solutions developed by Ontonix focus on countering what most threatens safety, advanced products, critical infrastructures, or IT network security - the rapid growth of complexity. In 2007 the company received recognition by being selected as Gartner's Cool Vendor. What makes Ontonix different from all those companies and research centers who claim to manage complexity is that we have a complexity metric. This means that we MEASURE complexity. We detect anomalies in complex defense systems without using Machine Learning for one very good reason: our clients don’t have the luxury of multiple examples of failures necessary to teach software to recognize them. We identify anomalies without having seen them before. Sometimes, you must get it right the first and only time!

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